*corresponding author #undergraduate researcher
Viewing: Organometallics | See All Publications
71 First and Second Sphere Interactions Accelerate Non-Native N-Alkylation Catalysis by the Thermostable, Methanol-Tolerant B12-Dependent Enzyme MtaC.
Kumar, A.; Yang, X., Li, J.; Lewis, J. C.* ChemComm, 2023, 59, 4798-4801.
See the original preprint on ChemRxiv.
Category: Biocatalysis | Organometallics
66 Cobalamin-Mediated Electrocatalytic Reduction of Ethyl Chloroacetate in Dimethylformamide
Gerroll, B. H. R.; Lewis, J. C.; Baker, L. A.* J. Electrochem. Soc. 2022, 169, 055501.
Category: Organometallics
61 Controlling Non-Native B12 Reactivity and Catalysis in the Transcription Factor CarH
Yang, X.; Gerroll, B. H. R.; Jiang, Y.; Kumar, A.; Zubi, Y. S.; Baker, L. A.; Lewis, J. C.* ACS Catal. 2022, 12, 935-942. Preprint available on ChemRxiv.
Category: Biocatalysis | Organometallics
57 Insight into the Scope and Mechanism for Transmetallation of Hydrocarbyl Ligands on Complexes Relevant to C-H Activation
Natalie Chan, Joseph J. Gair, Michael Roy#, Yehao Qiu#, Duo-Sheng Wang, Landon J. Durak, Liwei Chen#, Alexander S. Filatov, Jared C. Lewis*. Insight into the Scope and Mechanism for Transmetallation of Hydrocarbyl Ligands on Complexes Relevant to C-H Activation. Organometallics, 2021, 40, 6-10. You can read the originally submitted manuscript at ChemRxiv.
Category: Organometallics
56 Catalytic Behavior of Mono-N-Protected Amino Acid Ligands in Ligand-Accelerated C–H Activation by Palladium(II)
Salazar, C. A.; Gair, J. J.; Flesch, K. N.; Guzei, I. A.; Lewis, J. C.; Stahl, S. S.* Catalytic Behavior of Mono-N-Protected Amino-Acid Ligands in Ligand-Accelerated C-H Activation by Palladium(II). Angew. Chem. Int. Ed. 2020, 59, 10873-10877.
Category: Organometallics
54 Di-Palladium Complexes are Active Catalysts for Mono-N-Protected Amino Acid Accelerated Enantioselective C-H Functionalization
Gair, J. J.; Haines, B. E.; Filatov, A. S.; Musaev, D. G.*; Lewis, J. C.* Di-Palladium Complexes are Active Catalysts for Mono-N-Protected Amino Acid Accelerated Enantioselective C-H Functionalization. ACS Catalysis, 2019, 9, 11386-11397. This project originated from efforts to incorporate a Pd-MPAA catalyst into a protein scaffold to generate an ArM. Establishing the identity of such a catalyst proved far more difficult than we expected! The original manuscript, available at ChemRxiv, notes this origin story, which had to be removed during peer review.
Category: Organometallics
50 Synthesis, Characterization, and Theoretical Investigation of a Transition State Analogue for Proton Transfer During C-H Activation by a Rhodium-Pincer Complex
Gair, J. J.; Qiu, Y.#; Khade, R. L.; Chan, N.; Filatov, A. S.; Zhang, Y.*; Lewis, J. C.* A Heterobimetallic Isolobal Transition State Analogue for Proton Transfer During C-H Activation by a Rh-Pincer Complex. Organometallics, 2019, 38, 1407.
Category: Organometallics
44 (PNP)Rh complexes: Improved C-H Activation, Expanded Reaction Scope, and Catalytic Direct Arylation
Gair, J. J.; Qiu, Y.#; Chan, N.; Filatov, A. S.; Lewis, J. C.* (PNP)Rh complexes: Improved C-H Activation, Expanded Reaction Scope, and Catalytic Direct Arylation. Organometallics, 2017, 36, 4699-4706.
Category: Organometallics
41 Mono-N-Protected Amino Acid Ligands Stabilize Dimeric Palladium(II) Complexes of Importance to C-H Functionalization
Gair, J. J.; Haines, B. E.; Filatov, A. S.; Musaev, D. G.*; Lewis, J. C.* Mono-N-Protected Amino Acid Ligands Stabilize Dimeric Palladium(II) Complexes of Importance to C-H Functionalization. Chemical Science, 2017, 8, 5746-5756.
Category: Organometallics
27 Ir-Promoted, Pd-catalyzed Direct Arylation of Unactivated Arenes
Durak, L. J. and Lewis, J. C.* Ir-Promoted, Pd-catalyzed Direct Arylation of Unactivated Arenes. Organometallics, 2014, 33, 620-623.
Category: Organometallics
24 Transmetallation of Alkyl and Hydride Ligands From Cp*(PMe3)IrR1R2 to (cod)Pt/PdR3X
Durak, L. and Lewis, J. C.* Transmetallation of Alkyl and Hydride Ligands From Cp*(PMe3)IrR1R2 to (cod)Pt/PdR3X. Organometallics. 2013, 32, 3153-3156.
Category: Organometallics
22 Synthesis and Catalytic Activity of Amino Acids and Metallopeptides with Catalytically Active Metallocyclic Side Chains
Zhong, Z.; Yang, H.; Zhang, C.; Lewis, J. C. Synthesis and Catalytic Activity of Amino Acids and Metallopeptides with Catalytically Active Metallocyclic Side Chains. Organometallics, 2012, 31, 7328-7331.
Category: Organometallics
15 Rh(I)-Catalyzed Arylation of Heterocycles via C-H Bond Activation: Expanded Scope Through Mechanistic Insight
Lewis, J. C.; Berman, A. M. Bergman, R. G.*; Ellman, J. A.* Rh(I)-Catalyzed Arylation of Heterocycles via C-H Bond Activation: Expanded Scope Through Mechanistic Insight. J. Am. Chem. Soc. 2008, 130, 2493-2500.
Category: Organometallics
14 Rh(I)-Catalyzed Direct Arylation of Pyridines and Quinolines
Berman, A. M.; Lewis, J. C.; Bergman, R. G.*; Ellman, J. A.* Rh(I)-Catalyzed Direct Arylation of Pyridines and Quinolines. J. Am. Chem. Soc. 2008, 130, 14926-14927.
Category: Organometallics
13 Direct Functionalization of Nitrogen Heterocycles via Rh-Catalyzed C-H Bond Activation
Lewis, J. C.; Bergman, R. G.*; Ellman, J. A.* Direct Functionalization of Nitrogen Heterocycles via Rh-Catalyzed C-H Bond Activation. Acc. Chem. Res. 2008, 41, 1013-1025.
Category: Organometallics
11 Rh(I)-Catalyzed Alkylation of Quinolines and Pyridines via C-H Activation
Lewis, J. C.; Bergman, R. G.*; Ellman, J. A.* Rh(I)-Catalyzed Alkylation of Quinolines and Pyridines via C-H Activation. J. Am. Chem. Soc. 2007, 129, 5332.
Category: Organometallics
10 Microwave-Promoted Rhodium-Catalyzed Arylation of Heterocycles via C-H Bond Activation
Lewis, J. C.; Wu, J. Y.#; Bergman, R. G.*; Ellman, J. A.* Microwave-Promoted Rhodium-Catalyzed Arylation of Heterocycles via C-H Bond Activation. Angew. Chem. Int. Ed. 2006, 118, 1619-1621.
Category: Organometallics
9 Oldfield, E. NMR Shifts, Orbitals, and M...H-X Bonding in d8 Square Planar Metal Complexes
Zhang, Y.; Lewis, J. C.; Bergman, R. G.*; Ellman, J. A.*; Oldfield, E. NMR Shifts, Orbitals, and M...H-X Bonding in d8 Square Planar Metal Complexes. Organometallics 2006, 25, 3515-3519.
Category: Organometallics
8 Experimental and Computational Studies on the Mechanism of N-Heterocycle C-H Activation by Rh(I)
Wiedemann, S. H.; Lewis, J. C.; Bergman, R. G.*; Ellman, J. A.* Experimental and Computational Studies on the Mechanism of N-Heterocycle C-H Activation by Rh(I). J. Am. Chem. Soc. 2006, 128, 2452-2462.
Category: Organometallics
7 Preagostic R-H Interactions and C-H Bond Functionalization: A Combined Experimental and Theoretical Investigation of Rh(I) Phosphinite Complexes
Lewis, J. C.; Wu, J. Y.#; Ellman, J. A.*; Bergman, R. G.* Preagostic R-H Interactions and C-H Bond Functionalization: A Combined Experimental and Theoretical Investigation of Rh(I) Phosphinite Complexes. Organometallics 2005, 24, 5737-5746.
Category: Organometallics
6 Arylation of Heterocycles via Rhodium-catalyzed C-H Bond Functionalization
Lewis, J. C.; Wiedemann, S. H.; Bergman, R. G.*; Ellman, J. A.* Arylation of Heterocycles via Rhodium-catalyzed C-H Bond Functionalization. Org. Lett. 2004, 6, 35-38.
Category: Organometallics
Patents
3 Coelho, Pedro, S.; Brustad, Eric M.; Arnold, Frances H.; Wang, Z.; Lewis, Jared C. In vivo and in vitro olefin cyclopropanation catalyzed by engineered and chimeric heme enzyme.” PCT Int. Appl. WO2014058744, 2014.
