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A 3D-QSAR/CoMFA Study of the Activity of Bisphosphonates Against Trypanosoma brucei rhodesiense: Farnesyl Pyrophosphate Synthase as a Drug Target and Analysis of Drug Toxicity

Martin, M. B.; Sanders, J. M.; Kendrick, H.; de Luca-Fradley, K.; Yardley, V.; Lewis, J. C.#; Grimley, J. S.#; van Brussel, E. M.#; Olsen, J. R.#; Meints, G. A.; Burzyska, A.; Kararski, P.; Croft, S. L.; Oldfield, E.* A 3D-QSAR/CoMFA Study of the Activity of Bisphosphonates Against Trypanosoma brucei rhodesiense: Farnesyl Pyrophosphate Synthase as a […]

Bisphosphonates Inhibit the Growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: A Potential Route to Chemotherapy

Martin, M. B.; Grimley, J. S.#; Lewis, J. C.#; Heath, H. T. III; Bailey, B. N.; Kendrick, H.; Yardley, V.; Caldera, A.; Lira, R.; Urbina, J. A.; Moreno, S. N. J.; Docampo, R.; Croft, S.; Oldfield, E.* Bisphosphonates Inhibit the Growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: A Potential […]