Non-Native Site-Selective Enzyme Catalysis
Mondal, D.; Snodgrass, H. M.; Gomez, C. A.; Lewis, J. C.* Chem. Rev. 2023, 123, 10381-10431. See the original preprint available on ChemRxiv.
Mondal, D.; Snodgrass, H. M.; Gomez, C. A.; Lewis, J. C.* Chem. Rev. 2023, 123, 10381-10431. See the original preprint available on ChemRxiv.
Liu, B.; Zubi, Y. S.; Lewis, J. C.* Dalton, 2023, 52, 5034-5038. See the original preprint on ChemRxiv.
Zubi, Y. S.; Seki, K.; Li, Y.; Hunt, A.; Liu, B.; Roux, B.*, Jewett, M. C.*, Lewis, J. C.* Nat. Commun. 2022, 13, 1864. Preprint available on ChemRxiv. See peer review here.
Zubi, Y. S.; Liu, B.; Gu, Y.; Sahoo, D.; Lewis, J. C.* Chem. Sci. 2022, 13, 1459-1468. Preprint available on ChemRxiv.
Upp, D. M.; Huang, R; Li, Y.; Bultman, M. J.#; Roux, B.*, Lewis, J. C.* Angew. Chem. Int. Ed. 2021, 60, 2-7. You can read the original manuscript on ChemRxiv.
Lewis, J. C.* Beyond the Second Coordination Sphere: Engineering Dirhodium Artificial Metalloenzymes to Enable Protein Control of Transition Metal Catalysis. Accounts of Chemical Research. 2019, 52, 576-584. This manuscript was an invited contribution to a special issue of Accounts of Chemical Research on artificial metalloenzyme catalysis and non-native reactions catalyzed by natural metalloenzymes. Check out the […]
Ellis-Guardiola, K.; Rui, H.; Beckner, R.;# Srivastava, P.; Sukumar, N.*; Roux, B.*; Lewis, J. C.* Crystal Structure and Conformational Dynamics of Pyrococcus furiosus Prolyl Oligopeptidase. Biochemistry, 2019, 58, 1616. The studies detailed in this manuscript were originally reported on ChemRxiv. The ChemRxiv manuscript detailed how the large scale conformational dynamics outlined in the Biochemistry paper can be used to rationalize the […]
Yang, H.; Swartz, A. M.; Srivastava, P.; Ellis-Guardiola, K.; Park, H. J.; Upp, D.; Belsare, K.; Lee, G.; Zhang, C.; Moellering, R. E.; Lewis, J. C.* Evolving Artificial Metalloenzyme Selectivity via Random Mutagenesis. Nat. Chem. 2018, 10, 318-324.
Ellis-Guardiola, K.; Lewis, J. C.* Preparation of Artificial Metalloenzymes. In Artificial Metalloenzymes and MetalloDNAzymes in Catalysis. From Design to Applications; Diégues, M.; Bäckvall, J.-E.; Pàmies, O., Eds.; 2018, Wiley-VCH.
Kohler, V.; Schwizer, F.; Okamoto, Y.; Lebrun, V.; Reuter, R.; Pellizzoni, M. M.; Heinisch, T.; Gu, Yifan; Lewis, J. C.*; Ward, T. R.* Artificial Metalloenzymes: Reaction Scope and Optimization Strategies. Chemical Reviews, 2017, 118, 142-231.